pentobarbital will minimize the extent or effect of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
fentanyl transmucosal and pentobarbital both raise sedation. Keep away from or Use Alternate Drug. Restrict use to individuals for whom alternate remedy selections are inadequate
pentobarbital will decrease the level or result of fosaprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Monitor Intently (one)pentobarbital will decrease the extent or outcome of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Loss of, or decreased response to tofacitinib may perhaps manifest when coadministered with strong CYP3A4 inducers
pentobarbital will lessen the extent or impact of saxagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.
pentobarbital will decrease the extent or influence of irinotecan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the level or result of quetiapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
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Monitor Carefully (one)pentobarbital will reduce the extent or outcome of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Coadministration of fentanyl with CYP3A4 inducers may lead into a decrease in fentanyl plasma concentrations, insufficient efficacy or, possibly, growth of the withdrawal syndrome inside a client who may have created Bodily dependence to fentanyl. Just after stopping a CYP3A4 inducer, since the effects with the inducer decline, the fentanyl plasma focus will increase which could boost or extend both the therapeutic and adverse effects.
pentobarbital will lessen the level or result of sunitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Contraindicated (one)pentobarbital will minimize the extent or influence of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib can be a delicate CYP3A4 substrate. Coadministration with potent or average CYP3A4 inducers is contraindicated.
pentobarbital will lessen the extent or impact of rabeprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.
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pentobarbital will lessen the level or influence of sufentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.